PCT (Post-Cycle Therapy) is commonly discussed in the context of restoring hormonal balance after exogenous androgen exposure. During a “cycle,” endogenous testosterone output can down-regulate while aromatase activity may increase, influencing the balance between androgens and estrogens. When exogenous inputs are withdrawn, relative estrogen activity can remain elevated versus declining androgens. The overview below summarizes research and educational concepts used to describe strategies for managing these dynamics.