IGF-1 LR3 (Insulin-Like Growth Factor 1 Long R3) is a stabilized analog of the naturally occurring growth factor IGF-1. It remains under active research and experimental evaluation and is not approved for therapeutic use by any medical authority. This extended-sequence peptide is designed to resist degradation, prolong receptor interaction, and provide a reproducible reference model for IGF signaling studies.

EU Pharmaceuticals is pleased to include IGF-1 LR3 in its Platinum Research Range — a selection of high-purity peptides for advanced biochemical and receptor-binding investigations.

Scientific Background

IGF-1 LR3 differs from native IGF-1 by a 13-amino-acid extension at the N-terminus and a substitution of arginine for glutamic acid at position 3. These modifications reduce affinity for IGF-binding proteins, resulting in extended receptor availability during in-vitro testing.

• Investigated for cell-signaling dynamics related to growth and differentiation.
• Used in laboratory models to explore protein synthesis and nutrient-signaling pathways.
• Supports research into the IGF-1/PI3K/Akt and MAPK signaling cascades.

Product Composition

• Compound: IGF-1 LR3 (Insulin-Like Growth Factor 1 Long R3)
• Form: Lyophilized peptide powder for laboratory reconstitution
• Content: 100 mcg per vial × 10 vials
• Purity: ≥ 98 % (HPLC verified)

Kit Components

• 10 × 100 mcg vials of lyophilized IGF-1 LR3 (vacuum-sealed at +1 Pa)
• 1 × 10 mL acetic acid solution for reconstitution reference
• 2 × 10 mL bacteriostatic water for buffering
• 10 × 1 mL laboratory syringes for precise measurement and transfer

Laboratory Reconstitution Reference

For controlled research preparation, the lyophilized peptide can be dissolved using the supplied acetic acid solution, then buffered with bacteriostatic water to achieve the desired working concentration.

• Add acetic acid slowly along the vial wall; swirl gently until dissolved.
• Introduce bacteriostatic water to reach the intended final volume and pH balance.
• Label vials clearly with concentration and preparation date.
• Store refrigerated at 2–8 °C and avoid multiple freeze–thaw cycles.

Research Focus Areas

• IGF receptor-binding and intracellular signaling assays
• Cell proliferation and differentiation modeling
• Comparative analysis with native IGF-1 in controlled systems
• Studies of insulin-like growth factor stability and kinetics

Storage & Stability

• Lyophilized form: Store at −20 °C, protected from moisture and light
• Reconstituted form: 2–8 °C; use within 30 days for optimal stability

EU Pharmaceuticals Quality Commitment

EU Pharmaceuticals peptides are manufactured under controlled laboratory conditions with validated identity, purity, and sterility testing. Each batch is traceable and quality-assured to support reliable, reproducible research outcomes.

For laboratory, educational, and research use only. Not intended for human or veterinary administration, ingestion, or therapeutic use. No medical, performance, or genetic-modification claims are made or implied. Buyer is responsible for lawful handling, storage, and compliance with all regulations.