YK-11 (Steroidal SARM Class)
YK-11 is supplied as an analytical-grade reference compound used in studies investigating myostatin-related pathways, follistatin expression, and androgen receptor interactions. It is structurally classified as a steroidal selective androgen receptor modulator (SARM), often examined for its potential to influence muscle cell differentiation and myogenic signaling.
Analytical Profile
- Compound type: Steroidal SARM analogue
- Primary research focus: Myostatin inhibition and follistatin modulation
- Typical analytical models: in-vitro receptor-binding and transcriptional assays
- Half-life (research reference): ~6 – 10 hours (for comparative kinetics only)
Mechanistic Overview
YK-11 has been characterized in research literature as a partial androgen receptor agonist that may influence follistatin-mediated down-regulation of myostatin—a regulatory protein that limits skeletal-muscle growth. Reference studies explore how reduced myostatin activity can alter muscle-cell protein synthesis, fiber density, and gene transcription linked to anabolic signaling.
Observed Research Outcomes
- Changes in myostatin/follistatin expression ratios (cell-culture data)
- Potential increases in protein synthesis markers
- Enhanced cellular differentiation and contractile-fiber formation models
Composition (per tablet)
- 5 mg YK-11 (analytical grade)
- Standard excipient base, USP-grade
Packaging
- 56 tablets
Suggested Analytical Reference Range
- Male sample calibration: 5 – 15 mg equivalent (1 – 3 tablets)
- Female sample calibration: 2.5 – 5 mg equivalent (½ – 1 tablet)
- Comparative cycle length (research model): ~4 weeks
Stacking Reference (Laboratory Cross-Analysis)
- With MK-677 (Nutrobal) — Recovery marker comparison
- With GW-501516 (Cardarine) — Metabolic output studies
- With RAD-140 — Receptor synergy modeling
Storage & Handling
- Store in a cool, dry place (15 – 25 °C)
- Protect from moisture and direct light
For laboratory, research, and analytical use only. Not for human or veterinary application. No therapeutic or performance claims are made or implied. Buyer assumes full responsibility for lawful handling and use.
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