IGF-1 LR3 is a stabilized analog of insulin-like growth factor 1 designed for advanced research applications involving receptor interaction, intracellular signalling, growth-pathway modelling, and comparative analysis against native IGF-1. Its modified structure is intended to improve stability characteristics during controlled investigation and provide a more durable reference model for IGF-related laboratory work.

This kit is positioned for researchers seeking a more complete IGF-1 LR3 preparation format, with multiple lyophilized vials and supporting reconstitution components supplied together for controlled laboratory handling and repeat-use workflow.

Scientific Background

IGF-1 LR3 differs from native IGF-1 through a 13-amino-acid extension at the N-terminus and a substitution of arginine for glutamic acid at position 3. These structural modifications are associated with reduced affinity for IGF-binding proteins and extended receptor availability in controlled research settings.

As a result, IGF-1 LR3 is commonly selected for studies involving growth and differentiation signalling, protein synthesis and nutrient-signalling models, and investigation of the IGF-1 / PI3K / Akt and MAPK pathways.

Product Composition

• Compound: IGF-1 LR3 (Insulin-Like Growth Factor 1 Long R3)
• Form: Lyophilized peptide powder for laboratory reconstitution
• Content: 1mg per vial × 10 vials
• Purity: ≥ 98% (HPLC verified)

Kit Components

• 10 × 1mg vials of lyophilized IGF-1 LR3
• 1 × 10mL acetic acid solution for reconstitution reference
• 2 × 10mL bacteriostatic water for buffering
• 10 × 1mL laboratory syringes for measurement and transfer

Laboratory Reconstitution Reference

For controlled research preparation, the lyophilized peptide may be dissolved using the supplied acetic acid solution and then buffered with bacteriostatic water to achieve the intended working concentration.

• Add acetic acid slowly along the vial wall and swirl gently until fully dissolved.
• Introduce bacteriostatic water to reach the desired final volume and pH balance.
• Label each vial clearly with concentration and preparation date.
• Store refrigerated at 2–8°C after preparation and avoid repeated freeze–thaw cycles.

Research Focus Areas

• IGF receptor-binding and intracellular signalling assays
• Cell proliferation and differentiation modelling
• Comparative evaluation against native IGF-1
• Stability, kinetics, and signalling-duration studies

Storage & Stability

• Lyophilized form: Store protected from moisture and light
• Reconstituted form: Store at 2–8°C and use within 30 days for optimal stability

Quality Commitment

EU Pharmaceuticals peptides are prepared under controlled laboratory conditions with validated identity, purity, and sterility testing. Each batch is traceable and quality-assured to support reliable and reproducible research outcomes.

Important Notice

For laboratory, educational, and research use only. Not intended for human or veterinary administration, ingestion, or therapeutic use. No medical, performance, or treatment claims are made or implied. Buyer is responsible for lawful handling, storage, and compliance with applicable regulations.