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Sunday, 06 January 2013 09:17

Anti Estrogens - Post Cycle Therapy

A successful PCT  (Post Cycle Therapy) aims to control the balance of oestrogen and testosterone. While on a cycle, synthetic testosterone is supplemented and the bodies natural production cesses. The reason for this is the body will always attempt to keep it hormones in balance so when it identifies extremely high levels of testosterone, not only does it stop production thereof, it also increase production of oestrogen. It does this by releasing higher levels of the aromatase enzyme which converts some of the testosterone to oestrogen. When the gear is stopped, the synthetic testosterone levels drop relatively fast in comparison the oestrogen levels and therefore it’s important to understand what product does what, when it should be taken and how much. The following aims clarify this point is plain, simple english.

There are two way of controlling the quantity of estrogens and the effect thereof on your body.

  • Anti-estrogens
  • Oestrogen inhibitors

They work in two very different ways and yet yield a similar result depending on current estrogens levels and where you are in a cycle.

Oestrogen Inhibitor – “preventer”

These products bind to the aromatize enzyme and render it inactive (aromatize enzyme converts testosterone to oestrogen). Without the active aromatize enzyme, oestrogen cannot be produced and oestrogen production is effectively inhibited/stopped at the production site.

Advantage:
Prevents excess amounts of oestrogen from being produced

Disadvantage:
Does not remove oestrogen currently in the body and therefore it’s still absorbed.

Products:
Arimidex 01 (Anastrozole) 1mg every second day (EOD)
Proviron 25 (Mesterolone) 25 - 100mg per day (ED)
Letrozole 2.5 (also known as Femara) 2.5mg per day (ED)

Anti-estrogens – “control”

These products work by blocking the estrogen receptor. This type of product is typically used and recommended when there are already high levels of estrogens in your body and you may be showing effects of gyno. What this product does is bind itself to the estrogens receptor so when the estrogen gets to the receptor it’s already occupied by a weak or “fake” oestrogen. Note that these products do not prevent the conversion of testosterone to oestrogen which is why it’s advisable to use these products in conjunction with an oestrogen inhibitor.

Advantage:
Prevents oestrogen currently in the body from being used which means it stops the effect of oestrogen relatively quickly in comparison to an oestrogen inhibitor.

Disadvantage:
Does not control the production of oestrogen at all.

Products:
Clomid 50 (Clomifen) 50 - 100mg per day (use 100mg for first 7 days)
Nolvadex 20 (Tamoxifen) 20 - 40mg per day (use 20mg from day 8 for 30 days)

Application:

  • Suffering from Gynecomastia

You need to prevent the high levels of oestrogen already in your body from being absorbed by using an anti-oestrogen. 40mg of Nolvadex 20 is the preferred choice for quick results. Second, you need to prevent your body from over producing even more oestrogen by using an oestrogen inhibitor and in this case Arimidex 01 is recommended if you are currently on a cycle containing testosterone.

If you are suffering from sever gyno, Letrozole 2.5 is an excellent choice and is reported as one of the few products that can actually reverse gyno.

  • PCT (Post Cycle Therapy)

PCT is divided into the management of 2 parts

  • Oestrogen
  • Testosterone
    • Oestrogen management
      • Reducing oestrogen production – preventing oestrogen production.

Start Proviron 25 (100mg) 2 weeks prior to suggested PCT start date (see “When to start your PCT” below) in order to control / reduce the production of oestrogen and keep your libido in check. There should however still be sufficient estrogens in your system to stimulate GH output, upgrade the androgen receptor and improve glucose utilization. After a 2 week period the amount of produced oestrogen should be under control.

      • Reducing oestrogen absorption – controlling oestrogen that’s already produced.

The use of Clomid 50 for 7 days and Nolvadex 20 for 3 weeks (short-acting esters) or 5 weeks (long-acting esters) should prevent any rogue oestrogen from being used. Start dose high at 100mg for Clomid 50 and drop to 20mg Nolvadex 20. Continue the use of Proviron 25 during the PCT period but drop to 25mg per day for the last two weeks. FYI: it’s reported that Clomid may retain higher gains with side effects like mood swings, acne and impaired eyesight (possibly permanent) which is why we advise limiting its use to 7 days. Nolvadex 20 increase testosterone faster and has less side effects!

    • Testosterone management

In order to kick-start your testosterone take 500iu HCG when you start the Nolvadex 20 (ie one week after starting the anti-oestrogen phase) for one week and drop to 300iu in the second week. If long-acting esters have been used, continue with 300iu for an additional week.

NOTE: HCG is also useful during a cycle for the maintenance of testicular activity. For this purpose, 500iu every 5 days is recommended.

When to start your PCT

Take the steroid with the longest active life of your stack. Active life x 3 minus 14 days is when you should start your PCT for a period of 4 – 6 weeks. Starting before this time would mean that there is still to much activity from the product. So as an example, if deca-durabolin was used, PCT would start on day 45 – 14 = 31. (SEE HALF LIFE TABLE)

PCT example

Eg of long acting ester PCT – Deca Durabolin 350

Week

1

2

3

4

5

6

7

8

9

10

11

12

Prov25

 

 

 

 

100ED

100ED

50ED

50ED

50ED

50ED

25ED

25ED

Clom50

 

 

 

 

 

 

100ED

 

 

 

 

 

Nol20

 

 

 

 

 

 

 

20ED

20ED

20ED

20ED

20ED

HCG

 

 

 

 

 

 

 

500iuED

250iuED

 

 

 

  • Start day 31 (for 14 days)
    Proviron 25 x 100mg ED or Arimedex 5 x 0.5mg every second day – this will reduce oestrogen production down to a more normal level.
  • Day 45 (for 7 days)
    Proviron 25 x 50mg
    Clomid 50 x 100mg – this will block the oestrogen that has already been produced from being absorbed.
  • Day 52 (for 7 days)
    Proviron 25 x 50mg
    HCG x 500iu
    Nolvadex 20 x 20mg
  • Day 59    
    Proviron 25 x 50mg but drop to 25mg for last 14 days
    HCG x 300iu for 14 days (for 7 days-short acting ester / 14 days long acting ester)
    Nolvadex 20 x 20mg for 28 days (for 14 days-short acting ester / 28 days long acting ester)

 

Eg of short acting ester PCT : Durabolin NPP 125  (fast acting Deca)

Week

1

2

3

4

5

6

7

8

Prov25

 

 

100ED

100ED

50ED

50ED

25ED

25ED

Clom50

 

 

 

 

100ED

 

 

 

Nol20

 

 

 

 

 

20ED

20ED

20ED

HCG

 

 

 

 

 

500iuED

 

 

 

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